Adherence and management of possible side effects.
Side effects of antiretroviral drugs in pregnancy.
Side effects to the child.
The choice of an hiv regimen to use during pregnancy depends on several factors including a woman s current or past use of hiv medicines other medical conditions she may have and the results of drug resistance testing in general pregnant women with hiv can use the same hiv regimens recommended for non pregnant adults unless the risk of any known side effects to a pregnant woman or her.
Antiretroviral use is most risky for the child during the first trimester of pregnancy.
The following tables summarize the most common and most serious adverse events associated with antiretroviral medications used to treat hiv infection.
Increased risk of peripheral neuropathy when combined with stavudine.
Antiretroviral therapy art during pregnancy should focus on the reduction of perinatal transmission and the treatment of maternal human immunodeficiency virus hiv disease.
Art can reduce perinatal transmission by several mechanisms including lowering maternal antepartum viral load and preexposure and postexposure prophylaxis of the infant.
But if a person with hiv skips doses of these drugs the virus can start copying itself.
Drug toxicity during this time results in the most severe birth defects.
This is the time of organogenesis when the ectoderm endoderm and mesoderm form internal organs.